Bernadett Kalmar Selected Research

arimoclomol

1/2017	Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular Function.
3/2016	Targeting protein homeostasis in sporadic inclusion body myositis.
1/2014	The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol.
10/2008	Late stage treatment with arimoclomol delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS.
4/2004	Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice.

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Bernadett Kalmar Research Topics

Disease

7	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2018 - 01/2009
5	Disease Progression 01/2018 - 04/2004
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2017 - 01/2013
2	Mitochondrial Diseases (Mitochondrial Disease) 02/2022 - 01/2018
2	Hereditary Sensory and Autonomic Neuropathies (HSAN) 01/2021 - 01/2018
2	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 01/2017 - 06/2012
1	Necrosis 01/2019
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2018
1	Proteostasis Deficiencies 01/2017
1	Inclusion Body Myositis 01/2017
1	Muscular Diseases (Myopathy) 03/2016
1	Neoplasms (Cancer) 01/2013
1	Fatigue 09/2012
1	Atrophy 09/2012
1	Pathologic Processes 09/2011

Drug/Important Bio-Agent (IBA)

5	arimoclomolIBA 01/2017 - 04/2004
4	EnzymesIBA 01/2021 - 06/2012
4	Proteins (Proteins, Gene)FDA Link 01/2017 - 10/2008
4	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2014 - 04/2004
2	Serine C-PalmitoyltransferaseIBA 01/2021 - 01/2018
2	Protein Isoforms (Isoforms)IBA 01/2018 - 09/2012
2	Superoxide Dismutase-1IBA 01/2018 - 01/2014
2	Small Heat-Shock ProteinsIBA 01/2017 - 06/2012
1	Small Interfering RNA (siRNA)IBA 02/2022
1	1-deoxysphingolipidIBA 01/2021
1	LipopolysaccharidesIBA 01/2019
1	MetalsIBA 01/2018
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2018
1	CalciumIBA 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	RNA (Ribonucleic Acid)IBA 01/2017
1	Hydroxylamine (Hydroxylamine Hydrochloride)IBA 01/2017
1	Valosin Containing ProteinIBA 03/2016
1	Molecular Chaperones (Chaperone, Molecular)IBA 01/2013
1	LipidsIBA 01/2013
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 09/2012
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 09/2012
1	Myosins (Myosin)IBA 09/2012
1	Adenosine Triphosphatases (ATPase)IBA 09/2012
1	Cholinergic Agents (Cholinergics)IBA 06/2012
1	Biomarkers (Surrogate Marker)IBA 01/2012
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 04/2004
1	Alanine (L-Alanine)FDA Link 04/2004

Therapy/Procedure

3	Therapeutics 01/2017 - 09/2011
2	Denervation 01/2018 - 06/2012
2	Muscle Denervation 09/2012 - 06/2012